Decreased Hepatic P-Glycoprotein Expression Associated with Senecio Intoxication in Horses
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منابع مشابه
Oxymatrine inhibits development of morphine-induced tolerance associated with decreased expression of P-glycoprotein in rats.
The effect of oxymatrine on the development of tolerance to the antinociceptive effects of morphine was investigated in rats. The degree of tolerance was assessed using the tail-flick test before and after 6 days of twice daily administration of oxymatrine premorphine (10/20/30 mg/kg). High doses of oxymatrine inhibited the development of morphine tolerance (resembling the effect of 7.5 mg/kg o...
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The concept 'liver disease' includes several pathological conditions affecting liver's functions. It can either consist of a temporary impaired functioning of the liver and/or it can progress to its failure. The purpose of this review is to update the knowledge on hepatobiliary diseases and in particular on equine hyperlipaemia. Hepatobiliary disease's aetiology, clinical signs, diagnosis and n...
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OBJECTIVE Pancreatic-derived factor (PANDER, also named as FAM3B) is secreted by pancreatic α and β cells. Increasing evidence suggests that it may serve a hormonal function related to glycemic and lipid metabolism. In this study, we investigated the effects of PANDER overexpression on hepatic and adipose triglyceride metabolism in high-fat diet-fed male C57BL/6 mice. METHODS PANDER overexpre...
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ژورنال
عنوان ژورنال: Journal of Comparative Pathology
سال: 2009
ISSN: 0021-9975
DOI: 10.1016/j.jcpa.2009.08.135